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Promising Results from HIV Prevention Injection Study

South Africa
Promising Results from HIV Prevention Injection Study

A recent experiment showing the possibility of an injectable medication to prevent infections among high-risk people has given new hope in the fight against HIV. Compared to daily oral drugs Truvada and Descovy, the injectable lenacapavir revealed zero HIV infections in a study including nearly 5,300 adolescent girls and young women in South Africa and Uganda.

The research, carried out by the HIV Prevention Trials Network (HPTN) and supported by the Bill & Melinda Gates Foundation, marks a noteworthy advancement in HIV prevention. Principal investigator at the Wits Reproductive Health and HIV Institute Dr. Sinead Delany-Moretlwe stressed the significance of the results.

 “This is the first HIV prevention trial ever in history to show zero HIV infections with an intervention,” says Professor Thesla Palanee-Phillips, director of clinical trials at Wits RHI in a statement by Health-e News.

Dr. Linda-Gail Bekker, a leading researcher and CEO of the Desmond Tutu HIV Foundation, commented on the potential impact of this new method.

"The simplicity and efficacy of a bi-annual injection could address one of the major hurdles in HIV prevention – adherence to daily medication," she said in an interview with Health-e News​.

The lenacapavir trial's success gives hope for lowering these figures and boosting international HIV prevention initiatives. The potential impact on public health might be significant as researchers continue to analyse the data and plan for wider adoption, offering a new, more approachable preventive strategy for individuals who are most at risk.

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